Empirical Antifungal Therapy in Treating Febrile Neutropenic Patients
نویسندگان
چکیده
منابع مشابه
Empirical antifungal therapy in treating febrile neutropenic patients.
Persistent or recurrent unexplained fever in neutropenic patients receiving antibiotics can be caused by invasive fungal infections, which are often difficult to diagnose. Early trials of empirical antifungal therapy with amphotericin B deoxycholate (AmB) documented reductions in the frequency of and the morbidity and mortality associated with invasive fungal infections. Because of AmB's infusi...
متن کاملEmpirical versus preemptive antifungal therapy for high-risk, febrile, neutropenic patients: a randomized, controlled trial.
BACKGROUND Empirical antifungal therapy is the standard of care for neutropenic patients with hematological malignancies who remain febrile despite broad-spectrum antibacterial treatment. Recent diagnostic improvements may ensure the early diagnosis of potentially invasive fungal disease. Reserving antifungals for this stage may achieve similar survival rates and reduce treatment toxicity and c...
متن کاملPreemptive Antifungal Therapy for Febrile Neutropenic Hematological Malignancy Patients in China
BACKGROUND The aim of this study was to evaluate the efficiency, adverse effects, and pharmacoeconomic impact of empirical and preemptive antifungal therapy for febrile neutropenic hematological malignancy patients in China. MATERIAL AND METHODS Patients with febrile neutropenia during hematological malignancy were randomly divided into an empirical group and a preemptive group. The preemptive ...
متن کاملPreemptive antifungal therapy among neutropenic patients.
lated from sputum samples obtained from 7 patients were not considered to represent systemic infection. Five (16%) of the patients with VRE bacteremia had polymicrobial infections with Stenotrophomonas maltophilia (2 patients), Escherichia coli (1), Pseudomonas aeruginosa (1), and Staphylococcus aureus (1). Most patients (71%) were neutropenic (absolute neutrophil count, !500 cells/mL) when the...
متن کاملArticle: Oral vs. intravenous empirical antimicrobial therapy in febrile neutropenic patients receiving childhood cancer chemotherapy.
OBJECTIVE To compare the use of intravenous vs. oral antibiotic therapy. METHODS All febrile neutropenic patients younger than 18 years old with low risk of complications and receiving chemotherapy were selected. The study was conducted from 2002 to 2005 at the Pediatric Oncology Unit of Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil. Patients were divided into group A and group B...
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ژورنال
عنوان ژورنال: Clinical Infectious Diseases
سال: 2004
ISSN: 1058-4838,1537-6591
DOI: 10.1086/383052